Agios Nikolaos, capital of the Prefecture of Lasithi, is one of the most highly developed tourist towns in Greece. It lies along the west of the Mirabello bay. The main road axis of the island passes right outside the city limits, connecting it with  Iraklion to the west, Sitia to the east and Ierapetra to the south .

Agios Nikolaos  has one of the most spectacular landscapes in Greece.

The sea in Agios Nikolaos is superb and the surrounding area of the city is noted for its sandy beaches and beautiful bays.
The landmark of the city is a small lake, known as Voulismeni that is located in the center of the city, at the foot of the cliffs. Its shape is circular with a diameter of 137m.

Agios Nikolaos also possesses the second finest Archaeological Museum in Crete, where splendid archaeological findings from throughout the Prefecture of Lasithi are exhibited.